| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f79d07541953e2b144060cd6c5097df6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-717
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1998-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ec682f844301d5909096262474de3b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfd1669e2f230ae93447447003b6488a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3204d5ec0c704316804fc300386a9aa2 |
| publicationDate |
2002-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6479283-B1 |
| titleOfInvention |
Stimulation, culture and preservation of pancreatic cells |
| abstract |
A method for stimulating pancreatic cells to synthesize and/or excrete insulin comprises contacting insulin-producing cells, in particular their aqueous suspension, with a water-soluble cellulose derivative, in particular selected from alkylated, hydroxyalkylated, and alkylated-hydroxyalkylated cellulose or a mixture thereof. A medium for the culture of pancreatic beta-cells contains an effective cell-stimulating amount of a cellulose derivative. It can be used to stimulate pancreatic beta-cells to produce and/or excrete insulin. An apparatus for such stimulation comprises a container holding a solution of a cellulose derivative in an aqueous culture medium. Stimulation of pancreatic beta-cells by a cellulose derivative is useful in the management of diabetes. Further preservative or therapeutic methods using the aqueous cellulose derivatives are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8932858-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012178215-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011091427-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9476030-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013126590-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011041478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009227024-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011071107-A1 |
| priorityDate |
1997-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |