http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6472193-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb19557477a2bf3a8496b8761dcdff36 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42 |
| filingDate | 1999-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed512b7ac66be121e054569f32c6528 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27ecd346cd55d3a81d777f2aeae0e8f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6596ef2fa8f378c82ee2489faa9a486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18edac26024c14fb713bebbc299f3300 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa95e07f42bb993ad8693feea8ba939 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08ec075b50165c1159ec0a6a9605b1d2 |
| publicationDate | 2002-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6472193-B1 |
| titleOfInvention | Recombinant lysophosphatidic acid phosphatase |
| abstract | An object of the present invention is to provide a recombinant LPA phosphates capable of specifically hydrolyzing LPA, which is useful for elucidation of the metabolic pathway of LPA, and also for diagnosis and treatment of various diseases with which LPA is associated. The present invention also provides for a method capable of simply and inexpensively determining LPA associated with various diseases. The present invention also provides for a kit for determination suitable for the method. The present invention has succeeded in purifying the LPA phosphatase using bovine brain as a raw material, and further in cloning human LPA phosphatase gene. The present invention specifically relates to a DNA encoding a peptide comprising the amino acid sequence of SEQ ID NO:1; a DNA comprising the nucleotide sequence of SEQ ID NO:2; a protein encoded by the DNA; and expression vector carrying the DNA; a transformant harboring the expression vector; a method for producing a recombinant lysophosphatidic acid phosphatase by the transformant; a method for determination of LPA by the protein; a determination reagent for LPA by the protein; a kit for diagnosis, comprising the reagent for determination, and the like. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006084144-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003199054-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003190719-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005136515-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003180869-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005187379-A1 |
| priorityDate | 1998-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.