http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6468757-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-765 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate | 2001-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0cccefd6d79231da63babdd58cf9ecc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71acb3e0c7a4dbf34dff6140364cd85c |
| publicationDate | 2002-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6468757-B2 |
| titleOfInvention | Method for determining drug-serum protein binding |
| abstract | The present invention relates to a method of screening for drug binding to serum proteins by: preparing at least two solutions each including a concentration of a serum protein and a concentration of a candidate drug, wherein the concentration of the candidate drug is different for each of the at least two solutions; exposing each of the at least two solutions to a light source; measuring fluorescent emission by the serum protein or a serum protein-candidate drug complex for each of the at least two solutions upon said exposing; and determining whether a change in fluorescence emission is measured for an increased concentration of the candidate drug, wherein the change in fluorescence emission indicates binding of the candidate drug to the serum protein. A kit useful for performing a fluorimetric screening of drug binding to serum proteins is also disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7482162-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005112033-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004096900-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005003449-A1 |
| priorityDate | 2000-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.