| abstract |
This invention relates to an external patch for an antiinflammatory drug containing nonsteroidal antiinflammatory drug which is excellent in the dermal absorption and the skin adhesion, has hardly the skin stimulus. The nonsteroidal antiinflammatory drug composition comprised of nonsteroidal antiinflammatory drug, alkylpyrrolidone, hydrophilic polyethyleneglycol and hydrophilic nonionic surfactant was diffused in the water containing base comprised of water soluble polymer material, water soluble vinyl polymer and water insoluble multivalent metallic salt to provide the external patch containing nonsteroidal drug dissolved and diffused in the water containing base in the microemulsion state, which is excellent in the dermal absorption and also good in the skin adhesion, has hardly the skin irritations. |