| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22853c8669cb52e7d6fea1eea6467958 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-003 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
1999-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271ddd262e0098ffdb6f9504342996e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43359a83e382eb3b17dc6507e451379b |
| publicationDate |
2002-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6451579-B1 |
| titleOfInvention |
Regulated expression of recombinant proteins using RNA viruses |
| abstract |
The present invention describes cells and constructs for a regulated viral (e.g. alphavirus) expression system, where gene expression is controlled by controlling expression of replicases or nonstructural proteins and/or controlling the amount of such proteins introduced in a cell, which in turn regulates RNA replication and subsequently gene expression. Particularly, this system takes advantage of the high level expression of the alphavirus systems for recombinant protein production and allows for large scale applications without biosafety concerns. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7241617-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002012995-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009203883-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005158279-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003008399-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005106729-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8486693-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7947806-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10011847-B2 |
| priorityDate |
1998-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |