| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-36 |
| filingDate |
2000-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3daa1cae6c12277a17149c9fab9cdc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b3998868aeac6950afccd84db48ed29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9285893b481b80094c16420fe858a21e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21c392758f128c9e57e9a8f3061d9671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edc236997e74ca07de23174ccffb10bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79d9eab6a11371dc5dbef969101bcca2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_771980621d492b96bf74ac833a686958
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7170e6efbaf13880fe10db56f1c2430
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32f620d2f417be8d51c4083b6bc9231c |
| publicationDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6448413-B1 |
| titleOfInvention |
Process for the synthesis of a-nor-seco compounds with sterane skeleton |
| abstract |
The invention relates to a new process for the synthesis of 17beta-hydroxy-17alpha-methyl-1,3-seco-2-nor-5alpha-androstane-3-acid derivatives of formula (I)wherein the meaning of Z is carboxyl or formyl group andto the new secoindoxylidene carboxylic acid derivatives of formula (II)wherein R1 and R2 independently are C1-C4 alkyl or alkoxy group, hydrogen or halogen atom-which are intermediates for preparing the compounds of formula (I).The 17beta-hydroxy-17alpha-methyl-1,3-seco-2-nor-5alpha-androstane-3-acid derivatives of formula (I) are intermediates in the synthesis of oxandrolon (17beta-hydroxy-17alpha-methyl-2-oxa-5alpha-androstane-3-one), which is used as anabolic in therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005114842-A1 |
| priorityDate |
1999-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |