| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ef01e33058cf740cf2197991be97af1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2913 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G63-823
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F6-625 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F6-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-82 |
| filingDate |
2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_370b97e7cff912e7c9f641f6ce2364ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53292be926b567b3ac7e570388322fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7ea94cc9f4b4e3277acc640f4b6e669
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2536fe7625a100798b14103fb67c9240 |
| publicationDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6448367-B1 |
| titleOfInvention |
Method of producing poly(p-dioxanone), poly (p-dioxanone) monofilaments and method for producing the same |
| abstract |
The ring opening polymerization of p-dioxanone is started in a liquid phase under stirring at a temperature of 85 to 105° C. after adding 0.002 to 0.005 mol percent of stannous 2-ethylhexanoate forming a white crystal at a temperature of 0° C. as a catalyst and 0.01 to 0.1 mol percent of initiator. Stirring is stopped when a stirring load has increased by 10 to 100 percent over an initial load, while the temperature is lowered to a range of 65 to 85° C., to continue the polymerization in a solid phase to produce poly(p-dioxanone). The polymer is used to make a monofilament having a knot tensile strength of at least 30,000 psi and a strength retention of at least 58 percent after four weeks of immersion in a physiological saline solution at 37° C. The monofilament provides an absorbable surgical suture which is highly resistant to hydrolysis and very useful for stitching a wound or incision which requires a long time for healing. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114262950-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020109930-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11028222-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2520970-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03029301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6660813-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113166385-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113166385-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114262950-B |
| priorityDate |
1999-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |