abstract |
Disclosed are compounds of the formula:or pharmaceutically acceptable addition salts thereof wherein:Y represents oxygen or sulfur; Z is nitrogen or CH;R1, R2 and R3 independently represent organic or inorganic substituents;R4 and R4' independently represent hydrogen, alkyl or form a ring with the atom to which they are attached;R5 represents hydrogen, alkyl, alkoxy, or alkylthio, and R6 represents hydrogen or alkyl; or R5 and R6 form a ring together with the atoms to which they are attached; andR7, R8, R9, R10, and R11 independently represent hydrogen or alkyl,which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behavior, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents. |