| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b88d3bc25a6c3f27d97bc6d67b46b1ab |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 |
| filingDate |
1999-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeb5762a6bb2936700f43960bc6cb562
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_220a4bf56d30211f2e5884659843ccac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6d2caf5ce3d16c082443f02e99f9d28 |
| publicationDate |
2002-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6423342-B1 |
| titleOfInvention |
Process for the preparation of a solid pharmaceutical dosage form |
| abstract |
A process for the preparation of a solid pharmaceutical dosage form comprising a carrier and, as active ingredient, a compound which exists, in solution, in an equilibrium between a free acid or free base form and a salt form, and for which there is a difference in volatility between the free acid or free base form and the salt form. The process includes the steps of solidifying a mixture of the compound and carrier in a solvent, and subsequently removing the solvent from the solidified mixture. A pH modifier is added to the mixture prior to solidification to shift the equilibrium to favor the less volatile form of the active ingredient. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11559485-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11026883-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009247537-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8545879-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018069888-A1 |
| priorityDate |
1995-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |