http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6413951-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4180fc57a693864e2ce2dbfd64a9278 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-007 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00 |
| filingDate | 2001-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fa354b4518a79464064e5ea89ac36ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf65676ca5e83da58678b399f80a231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bc9571efaf04ea0baea6a9b86c21edf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9016664e630271b6450927bd5274654 |
| publicationDate | 2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6413951-B2 |
| titleOfInvention | 20-fluoro-17(20)-vinyl steroids |
| abstract | The invention relates to 20ξ-fluoropregna-4,17(20)-dien-3-on-21-oic acid ethyl ester, 20ξ-fluoro-3beta-hydroxypregna-5,17(20)-dien-21-oic acid ethyl ester, 20ξ-fluoro-21-hydroxypregna-4,17 (20)-dien-3-one, 20ξ-fluoropregna-5,17(20)-dien-3beta,21-diol and related compounds and to compositions incorporating these compounds, as well as the inhibition of C17,20 lyase, 5alpha-reductase and C17-hydroxylase, and to the use of these compounds in the treatment of androgen and estrogen mediated or dependent disorders, including benign prostatic hyperplasia, prostate cancer, breast cancer and DHT-mediated disorders such as acne and hirsutism. Treatment of disorders related to the over synthesis of cortisol, for example, Cushing's Syndrome are also included. The treatment of androgen-dependent disorders also includes a combination therapy with known androgen-receptor antagonists, such as flutamide. The compounds of the invention have the following general formulae: |
| priorityDate | 2000-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1014.