| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2a9d061bb94edb53550e546189b8d4a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2016-0036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2016-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J7-0445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2202-064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-8206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0085 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M16-142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M11-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M15-0066 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J7-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
| filingDate |
2000-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad3a0337a8fb04a341e4f3902a442436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ff96d4c13e29adf63742d542ecf851 |
| publicationDate |
2002-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6408854-B1 |
| titleOfInvention |
Insulin delivery enhanced by coached breathing |
| abstract |
The need for the delivery of insulin by injection can be reduced or eliminated by a method whereby an aerosolized insulin formulation is delivered to a patient's lungs and the rate at which the insulin is absorbed into the blood is increased by the use of an inhale-exhale breathing maneuver. Particles of insulin delivered to the surface of lung tissue will be absorbed into the circulatory system. The rate of absorption is enhanced by instructing the patient to inhale maximally and thereafter exhale maximally. This maneuver causes a spike in the rate at which insulin enters the circulatory system thereby increasing the rate at which glucose is removed from the circulatory system. The insulinmay be a dry powder but is preferably in a liquid formulation delivered to the patient from a hand-held, self-contained device which automatically releases an aerosolized burst of formulation. The device includes a sensor which is preferably electronic which measures inspiratory flow and volume which measurement can be used to control the point of drug release. The sensor can also assist the patient in the inhale-exhale maneuver. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9439907-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10857313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9545488-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE39847-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005274377-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11426536-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6647987-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10471222-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10610651-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9687487-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6650951-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8235037-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10307550-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004182383-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7987846-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211382-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9440034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004223917-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11065400-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8955512-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10350157-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11400241-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002124852-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11285275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8690856-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8823528-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7942147-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7981401-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8991387-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7645442-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11642473-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9370629-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7766013-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11273271-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008060644-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8936573-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7683029-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8387612-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8288372-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8333197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7913688-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9308208-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8074644-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10525214-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008264416-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004101481-A1 |
| priorityDate |
1993-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |