Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d669af06cb2abbcd6823699582a97002 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-00 |
filingDate |
2000-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e3d3a3f622198ad727bdff27f80ebb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_645d699dfaa01f0702785434e4903c38 |
publicationDate |
2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6399809-B1 |
titleOfInvention |
Process for the preparation of amino acid derivatives |
abstract |
Process for the preparation of amino acid derivatives of the general formula I n where R 1 -R 4 are as defined herein, n from the corresponding malonic acid monoester amides of the general formula II n by Hofmann degradation using a hypohalite in an aqueously basic medium, which comprises carrying out the reaction in the presence of an alcohol or amine and using the hypohalite in amounts of from 1.0 to 1.5 equivalents and the base in amounts of from 0.8 to 4.0 equivalents per mole of starting material II. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7550622-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005085544-A1 |
priorityDate |
1999-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |