| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-336
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-336 |
| filingDate |
2001-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a8aa00753d5dc436a26470a21151ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f427e20b001edbbad91935ecdacfc31 |
| publicationDate |
2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6399580-B1 |
| titleOfInvention |
Methods and compositions for stimulating tissue growth and epithelial moisturization |
| abstract |
The invention herein encompasses methods effective to stimulate epithelial cell proliferation and/or enhance epithelial moisturization and lubrication in a mammalian subject utilizing a composition comprising one or more inhibitors of beta-glucosidase activity or beta-glucocerebrosidase activity. The composition of the method may alternatively comprise a glycosphingolipid, particularly glucocerebroside, or a combination of the above inhibitor(s) and a glycosphingolipid. The method is effective to enhance the cosmetic appearance of skin and promote healing of skin and mucous membranes damaged or deficient from aging, traumatic wounds, photo-aging and a variety of atrophic conditions. The method may be applied to cells in culture. Also included in the invention is a composition comprising one or more inhibitors of beta-glucosidase and a glycosphingolipid useful to stimulate cell proliferation and enhance tissue moisturization and lubrication. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11708554-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11702634-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11685883-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005113769-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667876-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667881-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11773363-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634677-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11746319-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11624046-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629332-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008200611-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11613727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11608486-B2 |
| priorityDate |
1994-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |