http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6395759-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 |
filingDate | 1997-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e2891085705a953fdbe449b32019236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cca876413af4e3b23e39558b395db7b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62c1e5ca071e48c45cc532dc4414d5fd |
publicationDate | 2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6395759-B1 |
titleOfInvention | Substituted benzamide derivatives and pharmaceutical compositions containing them |
abstract | Compounds of formula (I) and pharmaceutically acceptable salts thereof, where G is a methylene or ethylene linkage; R1 is hydrogen, C1-6alkylO-; R2 is hydrogen, halogen, CN, N3, trifluoromethyldiazirinyl, CF3, CF3O-, CF3S-, CF3CO-, C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkylO-, C1-6alkylCO-, C3-6cycloalkylCO-, C3-6cycloalkyl-C1-4-alkylCO-, phenyl, phenoxy, benzyloxy, benzoyl and substituted benzoyl, phenyl-C1-4alkyl-, C1-6alkylSO2-, (C1-4alkyl)2NSO2- or (C1-4alkyl)NHSO2-; R3 is hydrogen, halogen, CN, N3, trifluoromethyldiazirinyl, C1-6alkylO-, C1-6alkylS-, C1-6alkyl, C3-6cycloalkyl, C3-6cycloalkyl-C1-4alkyl-, C1-6alkenyl, C1-6alkynyl, CF3CO-, C1-6alkylCO-, C3-6cycloalkylCO-, C3-6cycloalkyl-C1-4alkylCO-, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C1-4alkyl-, or -NR5R6 where R5 is hydrogen or C1-4alkyl; and R6 is hydrogen, C1-4alkyl, -CHO, -CO2C1-4alkyl or -COC1-4alkyl; R4 is hydrogen, C1-6alkyl, C1-6alkenyl, or C1-6alkynyl, are useful in the prevention and treatment of anxiety, mania, depression disorders associated with a subarachnoid haemorrhage or neural shock, the effects associated with withdrawal from substances of abuse such as cocaine, nicotine, alcohol and benzodiazepines, disorders treatable and/or preventable with anti-convulsive agents, such as epilepsy including post-traumatic epilepsy, Parkinson's disease, psychosis, migraine, etc. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535670-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007293503-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10287353-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8962598-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004180892-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7579340-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004073634-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005049286-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7319111-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7288538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385131-B2 |
priorityDate | 1996-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 226.