http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6395541-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2658d45a8e9c71b9598e2bf83242bab3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eb9e1f42a24303557aa44b3a0dbf873 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77ef6f20c11f369ce3d22876f7b9eae4 |
publicationDate | 2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6395541-B1 |
titleOfInvention | Methods for the identification of compounds capable of inhibiting HIV-1 viral replication employing murine cell lines expressing human topoisomerase I |
abstract | The present invention relates to therapeutic protocols and pharmaceutical compositions designed to target topo I for the treatment of HIV infection. The invention relates to therapeutic modalities and pharmaceutical compositions for the treatment of HIV-infection using human topo I and its interaction with HIV gag and RT as a target for intervention. The invention further relates to the use of human topo I to enhance the activity of RT. The present invention also relates to the expression of human topo I in transgenic animals, in particular mice, as a system to study the HIV life cycle and to screen agents for their ability to interfere with the HIV life cycle. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6743586-B2 |
priorityDate | 1996-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1635.