| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3b6e03a92d64f0e4893a8b297f7647 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18551
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5252 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02 |
| filingDate |
1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_436c085a069f0bb3130130f066700319
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0857a5507d3c5a6e849a2515447cb4c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2583095ece6c105fbbb10df120f43d8 |
| publicationDate |
2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6395469-B1 |
| titleOfInvention |
Inactivated respiratory syncytial viral vaccines |
| abstract |
An immunogenic composition capable of producing a respiratory syncytial (RS) virus specific immune response in a host immunized therewith comprises purified, inactivated RS virus which is substantially free from cellular and serum components and which is non-infectious, non-immunopotentiating, immunogenic and protective. The virus is grown on a vaccine quality cell line and harvested virus is purified under non-denaturing conditions to be substantially free from cellular and serum components. The purified RS virus is inactivated using beta-propiolactone, a non-ionic detergent, particularly n-octyl-alpha-D-glucopyranoside and n-octyl-betaD-glucopyranoside, or ascorbic acid. The immunogenic composition may be formulated as a vaccine for in vivo administration to a human host. The immunogenic composition also may be used in diagnostic applications. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009028902-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011150929-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8506968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010316673-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021070844-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007212376-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007087016-A1 |
| priorityDate |
1993-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |