Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3b6e03a92d64f0e4893a8b297f7647 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-1045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-116 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
1999-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c9b1a09135aca2ef9ad9dce94a3c9b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05e704c1e63a962c6842e084dbacf5ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2023fe793f05127fc2a2322768982170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eac0ec37f375362828010bff8b2c5155 |
publicationDate |
2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6391313-B1 |
titleOfInvention |
Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
abstract |
A multi-valent immunogenic composition confers protection on an immunized host against infection caused by both Haemophilus influenzae and Moraxella catarrhalis. Such composition comprises at least four antigens comprising at least one antigen from Haemophilus influenzae, and at least one antigen from Moraxella catarrhalis. Three of the antigens are adhesins. High molecular weight (HMW) proteins and Haemophilus influenzae adhesin (Hia) proteins of non-typeable Haemophilus and a 200 kDa outer membrane protein of Moraxella catarrhalis comprise the adhesin components while the other antigen is a non-proteolytic analog of Hin47 protein. Each component does not impair the immunogenicity of the others. The multi-valent immunogenic composition may be combined with DTP component vaccines, which may also include non-virulent poliovirus and PRP-T, to provide a component vaccine without impairment of the immunogenic properties of the other antigens. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003170657-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003171254-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005249747-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006159709-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10716847-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110662557-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2902495-A1 |
priorityDate |
1999-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |