http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6387656-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate | 1998-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c61a8ce46096b9a9533a472492edcd1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd6fc0c6029767d6bd48a8ad6ae513ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f56403c3d9b222b53f215265b8ae88c |
| publicationDate | 2002-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6387656-B1 |
| titleOfInvention | Gene encoding MNR2 and uses thereof |
| abstract | This invention provides an isolated nucleic acid molecule encoding a motor neuron restricted pattern, MNR2, protein. This invention provides an isolated nucleic acid molecule of at least 15 contiguous nucleotides capable of specifically hybridizing with a unique sequence included within the sequence of the nucleic acid molecule encoding a MNR2 protein. This invention provides a purified MNR2 protein, a polyclonal and monoclonal antibody directed to an epitope of an MNR2 protein. This invention provides a method of inducing differentiation somatic motor neurons which comprises expressing MNR2 protein in any neural progenitor cells. This invention provides a transgenic animal which expresses an MNR2 protein. This invention provides a pharmaceutical composition comprising a MNR2 protein and pharmaceutically acceptable carrier. This invention provides methods of treating subjects afflicted with an abnormality associated with a lack of normally functioning motor neurons, neurodegenerative disease, an acute nervous system injury and a neuromuscular disease which comprises contacting the subject with a pharmaceutical composition comprising a MNR2 protein and pharmaceutically acceptable carrier. This invention provides a functionally equivalent analog of MNR2 that induces or prevents MNR2 differentiation of neural progenitor cells. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8097596-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7312081-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7074771-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003104374-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002197678-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100393320-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7192916-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008119426-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004096089-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6955802-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7393686-B1 |
| priorityDate | 1998-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 278.