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publicationNumber US-6375946-B1
titleOfInvention Enhanced activation of natural killer cells using an NK cell activator and a hydrogen peroxide scavenger or inhibitor
abstract A method for providing activated natural killer (NK) cells comprising the steps of administering to a population of cells which includes lymphocytes and monocytes, an effective amount of an NK cell activating cytokine or a NK cell activating flavonoid, wherein said NK cell activating cytokine is not IL-2 or IFN-alpha; and administering a compound effective to inhibit the production or release of hydrogen peroxide selected from the group consisting of histamine, other H2 receptor agonists, and serotonin.
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