| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
1997-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f00c14c03f3685b8ade6af4bbc141d39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_190e01ec43b6480b88601a32e545068a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4dea863b71e23b7dea538622ac87ad0 |
| publicationDate |
2002-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6372219-B1 |
| titleOfInvention |
Parasite-derived anti-inflammatory immunomodulatory protein |
| abstract |
A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite Schistosoma mansoni . This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transciptionally down regulate the production of proinflammatory cytokines IL-1 α and IL-1 β. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005119897-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009094401-A1 |
| priorityDate |
1996-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |