| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 |
| filingDate |
2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef85550a7592d8378a4a8ff738198bed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_946df45fc914a8fb834a5bf6f6f686f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab70bbf64e5f81bf3bd44b7b4113ef66 |
| publicationDate |
2002-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6369095-B1 |
| titleOfInvention |
Indole-3-carbinol (13C) derivatives and methods |
| abstract |
The invention provides methods and compositions relating to novel bioactive derivatives of indole-3-carbinol (I3C), including pharmaceuticals comprising a pharmaceutically acceptable excipient and a compound of the general formula:which inhibits tumor cell growth. Methods of inhibiting targeted cell growth include contacting a target cell with a disclosed compound under conditions whereby the growth the target cell is inhibited, and methods for evaluating the growth inhibitory activity of the compounds include contacting a cell with an effective amount of the compound and measuring the CDK6 expression in the cell, wherein a reduction in CDK6 expression correlates with the growth inhibitory activity of the compound. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015042170-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10799479-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11458141-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10441569-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1321696-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9918965-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11337961-B2 |
| priorityDate |
1997-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |