| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1087f0ab4628f6c16b45356d409213de |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
1999-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a230a42895809b39c7efd58d15e864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_159e796f3beaff8dcedeca99057f797d |
| publicationDate |
2002-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6365357-B1 |
| titleOfInvention |
Methods and reagents for preparing and using immunological agents specific for P-glycoprotein |
| abstract |
This invention relates to immunological reagents and methods specific for a mammalian, transmembrane protein termed Pgp, having a non-specific efflux pump activity established in the art as being a component of clinically-important multidrug resistance in cancer patients undergoing chemotherapy. The invention provides methods for developing and using immunological reagents specific for certain mutant forms of Pgp and for wild-type Pgp in a conformation associated with substrate binding or in the presence of ATP depleting agents. The invention also provides improved methods for identifying and characterizing anticancer compounds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172855-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10292982-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107209101-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10543210-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10548893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11234978-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10898485-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013739-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9561227-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107209101-B |
| priorityDate |
1996-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |