http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6355651-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40a92325286ca98dbffa06d2c67ed064 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 2000-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ea6ea00d476098bf53ee8de2a9cff0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f09f89979fdb321d187f78260424d318 |
| publicationDate | 2002-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6355651-B1 |
| titleOfInvention | Certain pyrrolopyridine derivatives; novel CRF1 specific ligands |
| abstract | Disclosed are compounds of the formula:whereinAr is optionally substituted aryl or heteroarylR1 is hydrogen or alkyl;R7 is hydrogen or alkyl;R2 is hydrogen, halogen, alkyl or alkoxy; orR1 and R2 taken together with the ring to which they are attached form a 5-9 membered saturated or aromatic ring optionally having a hetero atom selected from oxygen, sulfur or nitrogen;R3 and R4 are independently hydrogen, alkyl, cycloalkyl, aryl or heteroaryl groups; orR3 and R4 together with the nitrogen atom to which they are attached form a 5-8 membered ring; andR5 is hydrogen, halogen, straight or branched chain lower alkyl having 1-6 carbon atoms, or straight or branched chain lower alkoxy or thioalkoxy having 1-6 carbon atoms,which compounds are highly selective partial agonists or antagonists at human Corticotropin-Releasing Factor 1 (CRF1) receptors and are useful in the diagnosis and treatment of treating stress related disorders such as post trumatic stress disorder (PTSD) as well as depression, headache and anxiety. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007004708-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007219232-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004171607-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007021429-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009195967-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7427630-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7253284-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007252244-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6670371-B2 |
| priorityDate | 1995-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 318.