http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6350859-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
filingDate | 1999-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2002-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be0a4315c141fce6f41e1edc51331641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ac305765dfb0ec8c0765ae220643e9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2b8e4480b48c8c73df2856fe35a16d0 |
publicationDate | 2002-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6350859-B1 |
titleOfInvention | Class BI and CI scavenger receptors |
abstract | Two distinct scavenger receptor type proteins having high affinity for modified lipoproteins and other ligands have been isolated, characterized and cloned. HaSR-BI, an AcLDL and LDL binding scavenger receptor, which is distinct from the type I and type II macrophage scavenger receptors, has been isolated and characterized and DNA encoding the receptor cloned from a variant of Chinese Hamster Ovary Cells, designated Var-261. dSR-CI, a non-mammalian AcLDL binding scavenger receptor having high ligand affinity and broad specificity, was isolated from Drosophila melanogaster. The isolated receptors are useful in screening for drugs that inhibit uptake of cholesterol in endothelial or adipose cells or macrophages, respectively. They are also useful as probes for the isolation of other lipoprotein receptors and in research the roles of these receptors. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004171073-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2691401-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2691401-A4 |
priorityDate | 1994-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.