Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-708 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
filingDate |
1997-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13ce4154585466663955521902b67676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6baf6031adac38020ec2bf6b9f2c838a |
publicationDate |
2002-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6350752-B1 |
titleOfInvention |
Carbon monoxide dependent guanylyl cyclase modifiers and methods of use |
abstract |
Disclosed herein are methods and associated compositions and medicaments directed generally to the control of cellular and neural activity and for selectively and controllably inducing the in vivo genetic expression of one or more naturally occurring genetically encoded molecules in mammals. More particularly, the present invention selectively activates or derepresses genes encoding for specific naturally occurring molecules such as proteins or neurotrophic factors and induces the endogenous production of such naturally occurring compounds through the administration of carbon monoxide dependent guanylyl cyclase modulating purine derivatives. The methods of the present invention may be used to affect a variety of cellular and neurological functions and activities and to therapeutically or prophylactically treat a wide variety of neurodegenerative, neurological, cellular, and physiological disorders. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9062089-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023402-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8236339-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006127501-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7989650-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008026984-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011237546-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006233890-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7964220-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006115542-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7968605-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9611286-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8389572-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007219120-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9163044-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007207217-A1 |
priorityDate |
1994-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |