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publicationDate 2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6342493-B1
titleOfInvention Crystallographically stable amorphous cephalosporin compositions and process for producing the same
abstract Processes are provided for the preparation of orally administrable, yellow and powdery compositions essentially consisting of particles composed of a homogeneous mixture of an amorphous Cefditoren pivoxil substance with a water soluble high-molecular additive. These compositions can be produced by dissolving crystalline Cefditoren pivoxil substance and the water-soluble high-molecular additive in an aqueous solution of an acid, then neutralizing the resultant solution, to co-precipitate the product, and drying the thus precipitated product, followed by recovering the product in the form of the above-mentioned particles.
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