| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
| filingDate |
1994-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c603152d63ba133b29c70f389171d4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c66c17ed9b3d28a678b73017482ce21f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b033bf33e73c9dde0f72ebb785ac67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54bd715940778048867d4d8e17152b44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc7d2e2e8bdb57b7b798d30b6cc6bf0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_860822705e7046fb18d5708501c3be00 |
| publicationDate |
2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6342390-B1 |
| titleOfInvention |
Lipid vesicles containing adeno-associated virus rep protein for transgene integration and gene therapy |
| abstract |
A composition for delivering at least one DNA sequence encoding a desired protein or polypeptide (such as a therapeutic agent) to a cell. The composition comprises an adeno-associated virus rep protein (or a nucleic acid sequence encoding an adeno-associated virus rep protein) and a genetic construct including at least one DNA sequence encoding a protein or polypeptide or genetic transcript of interest and a promoter controlling the at least one DNA sequence. The genetic construct also includes a first adeno-associated virus ITR or protein or derivative thereof and a second adeno-associated virus ITR or a portion or derivative thereof. The first and second adeno-associated virus ITRs or portions or derivatives thereof flank the at least one DNA sequence encoding the protein or polypeptide or genetic transcript of interest and the promoter controlling the at least one DNA sequence encoding the protein or polypeptide or genetic transcript of interest. Such a composition provides for integration of genetic material at a specific locus in the human chromosome, while minimizing the possibility of inadvertent inactivation of host genes and minimizing the possibility of viral contamination. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8278960-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076941-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021022208-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11447797-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010320997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016183297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005129661-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005201735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076794-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002012997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10946094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10087224-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998734-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016164920-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013130393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-779514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10214731-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007156232-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10293059-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008213222-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-779514-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021222682-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021079002-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019133818-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6821511-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015035190-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002192826-A1 |
| priorityDate |
1994-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |