| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9dda6a6e438b4f1f8a0652402fe3d4fe |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-829 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L12-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-805 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L12-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-805 |
| filingDate |
1999-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_446459c8c1a659a691d0881b72162c2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a07886c547e8ec622217b5dbf3a2e2b1 |
| publicationDate |
2002-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6340667-B1 |
| titleOfInvention |
Reptilian-derived peptides for the treatment of microbial infections |
| abstract |
The present invention provides compositions useful as antimicrobial agents which include reptilian hemoglobin, the alpha and beta chains of hemoglobin free of heme, fragments of said proteins or polypeptide fragments thereof and combinations thereof. The compositions exert antimicrobial activity against both bacteria and fungi that is comparable to known antimicrobial peptides from human neutrophils, cathepsin G and azurocidin. Sensitive organisms include Gram-negative bacteria such as Escherichia coli and Pseudomonas aerioginosa, and the fungus Candida albicans. Methods for preparing the compositions also are provided. |
| priorityDate |
1997-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |