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filingDate 1998-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2002-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6337073-B1
titleOfInvention Intranasal yellow fever vaccination
abstract The invention relates to vaccine preparations, pharmaceutical preparations and methods for inducing protective immunity in humans using a live, attenuated yellow fever virus of strain D17 preferably administered by an intranasal route of administration. The inventors have also developed an assay for detecting the induction of both the binding and neutralizing antibodies formed in a protective immune response in humans who have received an intranasal vaccine preparation of the kind described.
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