Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1998-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f988ac427451518eafc8c27db0345855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adacc125807812488afd4d54e248d910 |
publicationDate |
2001-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6326484-B1 |
titleOfInvention |
Nucleic acids encoding regulators of FGF-2 transcription (RFT) and variants thereof |
abstract |
The present invention is based on the discovery of genes which encode polypeptides are FGF-2 regulators of transcription (RFT). RFT-A, a negative regulator of transcription and RFT-A' and RFT-B, positive regulators of FGF-2 traniscriptionl are provided. Also included are methods for diagnosis of prognosis for a subject having or at risk of having a disorder associated with FGF-2 and for treatment of cell proliferative disorders associated with FGF-2. Screening methods for identifying a compound which affects RTT-A polypeptide or a variant of RFT-A polypeptide and for identifying proteins that bind to RFT-A polypeptide or a variant of RFT-A are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9474785-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10703788-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8999929-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10633424-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657075-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10364278-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10398759-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9808508-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9475856-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10159711-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9464126-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10293027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926355-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926356-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10174090-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542309-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925243-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9925241-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9550820-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10695404-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001006955-A1 |
priorityDate |
1998-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |