| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2993 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-04 |
| filingDate |
1997-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1261e36902d23ce795969988269b52f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2744cd166339d728ea1db5740643e248
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b46330ed371504adbb5fac0c6712efc8 |
| publicationDate |
2001-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6313247-B1 |
| titleOfInvention |
Cinchonan based chiral selectors for separation of stereoisomers |
| abstract |
Enantioseparation methods using chemical compounds which contain the chiral 9,11-substituted-10,11-dihydro-cinchonan skeleton (9,11-Subst.-DHC) and the precursors thereof with the 9-substituted cinchonan skeleton (9-Subst.-C) are described and discussed. The chiral compounds of the present invention are based on cinchonan derivatives containing amide structure elements which support effectively and co-operatively the enantioseparation of chiral acidic selectands involving also ion-pair and ion-exchange binding mechanism between the strong amino group of the selector and the acidic group of the selectand. The methods of enantioseparation of the present invention are related to stereoselective liquid-liquid and liquid-solid type extraction principles and fractionated crystallization employing cinchonan derivative type selectors. In one embodiment of the present invention the chiral selector is immobilized onto support material or is incorporated within a polymer or is part of a polymer used for liquid-solid enantioseparation techniques. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012220729-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013138413-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010094210-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111377851-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111377851-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005136195-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9376431-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7258236-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003166654-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102059105-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6780861-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102059105-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102325779-A |
| priorityDate |
1996-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |