Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d054b5702fed9bd0aa96412f4649512 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0004 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate |
1998-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fdec91444d5f81d936b3b5a3a4526dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80dd9bbfe08111d39adff1223a219754 |
publicationDate |
2001-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6309851-B1 |
titleOfInvention |
Method for producing a recombinant protein |
abstract |
A method to inhibit the function of a class of bacterial periplasmic oxidoreductase enzymes, exemplified by TcpG of Vibrio cholerae , DsbA of E. coli , and Por of Haemophilus influenzae , is disclosed. A screening method to determine whether a chemical inhibits the function of the oxidoreductase enzymes is disclosed. Mutant bacteria lacking the ability to produce a functional periplasmic oxidoreductase and a cloned expression vector overproducing TcpG are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9045776-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708626-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6656468-B1 |
priorityDate |
1991-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |