Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b051f9f7933c758e66f6ceda5c9fb2cc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-307 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 |
filingDate |
2000-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_511a72247fe96f6efb000292617247f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e36f0f446ee6121bcf602a4e877c7b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f88578f6037e14ee433ae127273c7855 |
publicationDate |
2001-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6307105-B1 |
titleOfInvention |
High purity preparation of fluorinated 1,3-dicarbonyls using BDM (bis-fluroxy difluoromethane) |
abstract |
A process for providing an α-fluorinated-β-dicarbonyl includes electrophilically fluorinating a β-dicarbonyl with bis-fluoroxydifluoromethane in the presence of an acid to provide the α-monofluorinated-β-dicarbonyl. The acid is preferably hydrofluoric acid. Preferred β-dicarbonyls include methyl-3-oxopentanoate and ethyl-4,4,4-trifluoroacetoacetate. The process can limit radical impurity byproducts to no more than 4% in some cases, and less than 0.5% in other cases. Theoretical yields of 95% α-monofluorinated-β-dicarbonyl are possible in some cases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010305345-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101874013-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8350082-B2 |
priorityDate |
2000-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |