| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
| filingDate |
1998-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ecef59c691ec8d7339b24ca0fa7004d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e7b9dffcb194917031ab80cfff14ce9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3cdf987935bb8eef49addbb9d259a3d |
| publicationDate |
2001-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6303788-B1 |
| titleOfInvention |
Process for preparing omeprzole |
| abstract |
The present invention relates to a novel process for the synthesis of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, known under the generic name omeprazole. Moreover, the present invention also relates to manufacture of a pharmaceutical preparation thereof and its use in medicine. n The novel process for the preparation of omeprazole, comprises the step of oxidizing 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole in an organic solvent with an oxidizing agent in the presence of a titanium complex and optionally in the presence of a base. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7683178-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006040635-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7227024-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006084811-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010222591-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7915422-B2 |
| priorityDate |
1997-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |