http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6291463-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40a92325286ca98dbffa06d2c67ed064 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-82 |
| filingDate | 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b74a065b5375f93a2dd983d3082b8fb0 |
| publicationDate | 2001-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6291463-B1 |
| titleOfInvention | 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands |
| abstract | Disclosed are compounds of the formula:or pharmaceutically acceptable addition salts thereof wherein:R1 and R2 are the same or different and represent hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, hydroxy, amino, mono- or di(C1-C6)alkylamino, cyano or trifluoromethyl;Ar represents aryl or heteroaryl, each of which is optionally substituted with R3, R4 and/or R4;R3, R4, and R6 independently represent hydrogen, halogen, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, perfluoro(C1-C6)alkyl, perfluoro(C1-C6)alkoxy, or SO2NH2; orR3 and R4 together with the atoms to which they are attached represent a ring having 5-7 atoms; andR5 represents hydrogen or C1-C6 alkyl,which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behavior, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753811-A |
| priorityDate | 1998-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 329.