| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f04a7ba9ad27bfa7a635ed80c743be5a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8813
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-805
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25125 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6878 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
1997-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6738afa9eceff1c68f731e2cedb3d54b |
| publicationDate |
2001-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6291189-B1 |
| titleOfInvention |
Methods for the high-resolution identification of solvent-accessible amide hydrogens in polypeptides or proteins and for characterization of the fine structure of protein binding sites |
| abstract |
The present invention provides methods whereby the positions of peptide amide groups that are labeled with a heavy hydrogen in a polypeptide or protein can be localized at high resolution. The methods are useful for determining which peptide amide groups in a polypeptide or protein are accessible to solvent, mapping the binding site and/or binding surface of a binding protein, and/or studying allosteric or other conformational changes in a polypeptide or protein which alter the rates at which certain peptide amide hydrogens exchange with solvent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6599707-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010120895-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006166273-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708401-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03034177-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03034177-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1578950-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1578950-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005233406-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7368290-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02061047-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007093966-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9093254-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02061047-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003167159-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007087448-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004229369-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7280923-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012020143-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002182649-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945553-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7363171-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007122864-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002197650-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004153256-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10358490-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10358489-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9783606-B2 |
| priorityDate |
1994-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |