| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a6a9431aa1fe5109ca95ad4e332231b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11d05e40924c78e685d633fda269401b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 |
| filingDate |
1998-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_772b2951ba5a67e4ea6552807aaf51fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4a77b69a3a41aaae850674e1fbb3106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_071c88386fb1bd04a7c2517c29fa8c0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22175284882809270b7216140f6e1820
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d47cbd2d073526e981d78d15bfabfcd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_712331d9c8b52d35ae9f5f1902e08c70 |
| publicationDate |
2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6287844-B1 |
| titleOfInvention |
Compositions and methods for controlling genetically engineered organisms |
| abstract |
Compositions and methods for the control of genetically engineered organisms are described. A more effective cell suicide approach is contemplated based on the conditional expression of the lethal Streptomyces avidinii streptavidin gene. Toxicity of streptavidin is derived from its exceptionally high binding affinity for an essential prosthetic group, D-biotin. The general requirement for biotin through the living world makes streptavidin-based conditional lethal designs applicable to a broad range of containment strategies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8409796-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233451-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8137910-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004053411-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9267145-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9856476-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004072206-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9850485-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6660229-B2 |
| priorityDate |
1997-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |