| abstract |
An endoscopic tissue staining composition comprises carbon and suspending/viscosity-increasing agent in a pharmaceutically acceptable delivery vehicle. In an embodiment, the composition includes carbon black, activated carbon or unactivated carbon, suspending/viscosity-increasing agent, anti-foaming agent and surfactant. In a particular embodiment, the composition includes n 0.01% to 1.0% carbon, n 5.0% to 25% suspending/viscosity-increasing agent such as glycerol, n 0.005% to 0.05% anti-foaming agent such as simethicone, n 0.5% to 1.5% surfactant such as polyoxyethylene sorbitan esterified with fatty acid, and water. n A method for staining of internal sites, particularly in the mucosal layers of the gastrointestinal tract, urinary bladder or lungs, includes injecting the composition in staining amount in proximity to the internal site. A kit includes the composition packaged with a means for endoscopic injection, preferably a syringe and sclerotherapy needle. |