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filingDate 1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2001-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2001-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6271202-B1
titleOfInvention Reduction of impairment of respiratory tract mucosal immunity
abstract The present invention describes methods for reducing the impairment respiratory tract mucosal immunity associated with a lack of enteral feeding or a lack of immunological stimulation of the gastrointestinal tract comprising administering a therapeutically effective amount of a neuropeptide. Also described are methods for reducing the rate of infection of the respiratory tract by pathogenic microorganisms associated with a lack of enteral feeding or a lack of immunological stimulation of the gastrointestinal tract comprising administering a therapeutically effective amount of a neuropeptide. In addition, a method of reducing the atrophy or dysfunction of the GALT comprising administering a therapeutically effective amount of a neuropeptide is described. The specification further describes compositions for reducing or preventing the impairment of intestinal or respiratory tract mucosal immunity comprising a neuropeptide and a pharmaceutically acceptable carrier.
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