| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_849b911cd7cbdf4376e75df5b8711342 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| filingDate |
1999-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d789a23b377fae76a02b5d00723099f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6d4c307a465882bad1da2c0e686e9b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7f7df14836bd7af6a9d4d853f6c776c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34c7521e05d99b03ab510b444b49904a |
| publicationDate |
2001-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6268178-B1 |
| titleOfInvention |
Phage-dependent super-production of biologically active protein and peptides |
| abstract |
This invention relates to a method for enhancing the production of biologically active proteins and peptides in bacterial cells by infecting bacterial cells of the producer strain, which contain a plasmid with one or more targeted genes, with bacteriophage lambd with or without the targeted gene(s). The phage increases synthesis of the targeted protein and induces lysis of the producer strain cells. Super-production is achieved by cultivating the producer strain cells under culture conditions that delay lytic development of the phage. The biologically active proteins and peptides subsequently accumulate in a soluble form in the culture medium as the cells of the producer strain are lysed by the phage. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0214471-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001044133-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0214471-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6642026-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7252818-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004115769-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6794162-B2 |
| priorityDate |
1999-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |