http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6255120-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb9db3864b115c793e9c73626666c8bb |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
filingDate | 1998-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2001-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca46c5a02316f641cabfb270bbdd598c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ea12c82d3499dc1557598d8f975c611 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e88a1f4b8e9009a2b7e09b87b6e7067 |
publicationDate | 2001-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6255120-B1 |
titleOfInvention | Combinatorial library of substituted statine esters and amides via a novel acid-catalyzed rearrangement |
abstract | A combinatorial chemical library comprising a plurality of members of the Formula [S]-C(O)-L'-Z containing hydroxyamides is disclosed, in which [S] represents a solid support and L'-Z is a linker/compound residue. In this library, Z isand Y is -NR3R4 or -OR9. R3 and R4 are independently selected from the group consisting of H, alkyl, aralkyl, heteroarylalkyl, heterocycloalkyl, -CH(R5)CH(R6)OH, -CH(R5)C(O)NHR6 and -CH(R5)C(O)NHCH(R6)C(O)NHR7. R3 and R4 together arewherein X=O or NR8 and R9 is aryl, aralkyl or R7CH=CH(CH2){overscore (n)}. The combinatorial library can be optionally encoded with identifiers T'-L, which are covalently attached to the solid support. The methods of synthesizing such a library are described. The use of such library in assays to discover biologically active compounds is also disclosed. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003211965-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004214232-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2565275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005009743-A1 |
priorityDate | 1997-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1565.