http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6242231-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-11002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate | 1998-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2001-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec012c705dd106b9dbb416fc9fba3e58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0f4627a9e8b740e1b9fc2291fe5b1f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc5ceabb4ecdd50303bada2fb441919a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c5c208af31699543191837fc763a929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57eee6d1ad1e2e52a87e7600c82e3083 |
publicationDate | 2001-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6242231-B1 |
titleOfInvention | Process for producing trans-4-hydroxy-L-proline |
abstract | An industrially applicable process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is converted into trans-4-hydroxy-L-proline in the presence of an enzyme source which is derived from a microorganism belonging to the genus Dactylosporangium, Amycolatopsis or Streptomyces and which catalyzes the hydroxylation of L-proline into trans-4-hydroxy-L-proline, a divalent iron ion and 2-ketoglutaric acid, in an aqueous medium, and the produced trans-4-hydroxy-L-proline is collected from the aqueous medium. Also provided is a novel enzyme L-proline-4-hydroxylase which is useful for the process, a gene of L-proline-4-hydroxylase which is useful for the process, a transformant containing the gene, and a process for producing L-proline-4-hydroxylase using the transformant. In addition, provided is a process for producing L-proline-4-hydroxylase using the transformant which contains the gene and has a reinforced proline biosynthesis activity. |
priorityDate | 1993-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.