| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-4266
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-472 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-42 |
| filingDate |
1998-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bee69b560c8eef546c273bd31b01577 |
| publicationDate |
2001-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6238667-B1 |
| titleOfInvention |
Method of affinity cross-linking biologically active immunogenic peptides to antibodies |
| abstract |
A method of affinity cross-linking a peptide to an antibody by photo-chemically activating an azido compound in a peptide including said azido compound; adding an antibody to the photochemically activated peptide; and allowing the photochemically activated peptide and the antibody to react. The azido compound has an affinity for a hydrophobic structure in the variable domain of the antibody which binds to nucleotides or nucleosides, binding the peptide into a native binding pocket of the immunoglobulin (Ig) structure of an antibody. The site of cross-linking is located away from the antigen binding site in the Fv domain avoiding the compromise of antigen recognition. A composition of a peptide cross-linked to an antibody is also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005287154-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7569674-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013040309-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7393531-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009208418-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11116848-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008260635-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011229415-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006119291-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003113279-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004185039-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008213171-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7468254-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005063967-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2891666-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005033033-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197328-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10973826-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9547007-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2298806-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009098045-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006165618-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003166569-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8252902-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003175921-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004066917-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3301114-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007065398-A1 |
| priorityDate |
1997-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |