Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c8d4dc7bd1a30d8fda907fceaeb4e69 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8114 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-15 |
filingDate |
1996-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_210b638224992ff368d790a3d8e454f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f33f172e31c0b913b3d8b4cbc09050a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6c8c71722210f6c3fed88f809aa6353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51134c0f9ba905642da8d2aa9cddca63 |
publicationDate |
2001-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6225081-B1 |
titleOfInvention |
Protein, DNA coding for same and method of producing the protein |
abstract |
A novel protein having inhibitory activity on the protease activity of hepatocyte growth factor (HGF) activator was purified and isolated, and its molecular weight (ca. 40,000 daltons) and its N-terminal and partial amino acid sequences were determined. A gene coding for the protein was cloned, and the gene DNA was incorporated into a vector, for transforming host cells. Cultivation of the transformant gave the desired protein. The protein can be used as an in vivo or in vitro control factor for HGF or HGF activator. It is also useful as an antigen to be used in producing an antibody to be used as means for kinetic studies of the protein, or as a standard in assay systems therefor. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7589172-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003138896-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7087391-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004132660-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003064420-A1 |
priorityDate |
1995-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |