http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6221658-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 1999-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d560050ae1478138f0646c6ae284cb0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02beb1b670c6897e4628aafb871224f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7368dd4728d9b271c32460adec8c5fd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c2ec3ae97e393d4256216af79ff9e6 |
| publicationDate | 2001-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6221658-B1 |
| titleOfInvention | Diacylglycerol kinase isoforms epsilon and zeta and methods of use thereof |
| abstract | Two novel diacylglycerol kinase (DGK) isoforms are disclosed. The cDNA of one DGK isoform, designated DGKepsi, is about 2.6 kb in length. The DGKepsi cDNA has an open reading frame encoding 567 amino acids and has a predicted molecular mass of 63 kDA. DAG kinase epsi is highly selective for arachidonate-containing diacylglycerol (DAG) substrates. The cDNA of the second isoform, designated DGK ζ, is 3.5 kb in length. The DGKζ cDNA contains a single large open reading frame encoding a 928-amino acid protein with a predicted molecular mass of 103.9 kDa. An alternatively spliced muscle specific species of DGKζ, DGKζ-2 is also disclosed and characterized. DGKζ is localized to the nucleus. A lysine-rich region with homology to the MARCKS protein is shown to be necessary and sufficient to confer nuclear localization to DGKζ via a protein kinase C phosphorylation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004094598-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004094598-A3 |
| priorityDate | 1996-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1061.