Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-545 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
filingDate |
1997-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e91d70573cd8c520e6f52a915918e93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60c7561083804ac054bbe6557be6c57e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e549ebd59635319c5be06a55a3a3f4d |
publicationDate |
2001-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6214572-B1 |
titleOfInvention |
Programmed cell death and ICH-3 |
abstract |
This invention relates to modulation of programmed cell death. It also relates to transgenic non-human animals comprising a disrupted Ich-3 gene and methods of making these animals. The Ich-3 mutant animals exhibit resistance to septic shock and defects in follficulogenesis. This invention also relates to methods of using the transgenic animals to screen for compounds to treat septic shock and defective folliculogenesis. Moreover, this invention also relates to methods of treating septic shock in normal individuals by inhibiting ICH-3. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7569351-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004038243-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6867237-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6642368-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7052899-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003064952-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7968523-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006115496-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1633311-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7872112-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206738-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7166467-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003194393-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7611884-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007059831-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7396909-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010266581-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1633311-A4 |
priorityDate |
1996-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |