Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
filingDate |
1998-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f434d58cc2826da121c43907d073bb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a656c4c5a8e75054c762e2eb5e1f85d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6131f5be3781df7b7c11a441288fef8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4492e3f16d98253dc1b90e7036801163 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e9e17f40cba26ef0b294ec5c89cb48d |
publicationDate |
2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6201118-B1 |
titleOfInvention |
Process for forming an N-acylated, N,N-containing bicyclic ring from piperazic acid or an ester thereof especially useful as an intermediate in the manufacture of a caspase inhibitor |
abstract |
The invention relates to a process for simultaneously N(2)-acylating piperazic acid or an ester thereof and forming a bicyclic ring structure. The invention also relates to the use of that process step in a method of synthesizing a bicyclic compound useful as an intermediate for the production of an inhibitor of a caspase, particularly an inhibitor of interleukin-1beta converting enzyme ("ICE"). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005122682-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3444011-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006293517-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8828950-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6548664-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015175381-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004116355-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011212056-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022123062-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6716818-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008207605-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008207569-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003181388-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005122682-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005233974-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6495522-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2853901-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017079566-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010292174-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6620782-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017117478-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004078761-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1468993-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012049646-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018065902-A1 |
priorityDate |
1998-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |