| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d17ff54f3706245b8e25f8b0d22316cf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-7051 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
1998-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e85937177383c336b0d7b51f3da5140 |
| publicationDate |
2001-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6197531-B1 |
| titleOfInvention |
Method for determining the immunocompetence of a mammal and therapies related thereto |
| abstract |
A method for determining the immunocompetence of a mammal is described. Bodily fluid having T cell receptor complexes from a mammal is provided. Expression of a first component and a second component of the T cell receptor complexes is evaluated. An abnormal ratio of the number of cells expressing the first component as compared to the number of cells expressing the second component indicates altered immunocompetence in the mammal. Also described are methods for monitoring a therapeutic treatment of a disease in a mammal associated with an abnormal level of a T cell receptor complex component, methods for assessing the progression of a disease in a mammal associated with an abnormal level of a T cell receptor complex component, methods for predicting the prognosis of a mammal having a disease associated with an abnormal level of a T cell receptor complex component, methods for determining if a mammal is at risk for AIDS, methods for evaluating an agent for use in treating HIV infection, and methods for treating HIV infection in a mammal. Pharmaceutical compositions and kits are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3072901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2586461-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009125408-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2568289-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10914743-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2679596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3187585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2873423-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007147630-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009269773-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010291120-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9085641-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007147630-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2474146-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012170765-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9188588-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1870420-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009172826-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2848937-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02090550-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02090550-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011124017-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3069730-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016209424-A1 |
| priorityDate |
1997-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |