Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43509 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
1998-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4abdaf54524422fc3422b5a104672d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac1ae58ab4876c7afbf17bf03621d641 |
publicationDate |
2001-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6191114-B1 |
titleOfInvention |
Immunological activity for a peptide of the limulus anti-LPS factor |
abstract |
The present invention relates a novel immunological effect of one peptide from Limulus anti-LPS factor protein. The immunological effect are, (1) induce an antiviral state in both the Hep-2 and MDBK cell lines, (2) Supernatant from human mononuclear cells stimulated with peptide Limulus anti-LPS factor (LALF) is able to induce antiviral effect on Hep-2 cell line by mean of IFN-gamma (3) LALF peptide is able to modulate the immune response in vitro and in vivo. The present invention can be used in therapeutic and/or prophylactic treatment regimens of humans and animals to enhance their immune responses, without stimulating the production of certain biochemical mediators (e.g., TNF-alpha,) that can cause detrimental effects, such as fever and inflammation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7758533-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7291122-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006163138-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008110830-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7520992-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7524420-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005029193-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8633164-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004199099-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004173530-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011105416-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007095867-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006129082-A1 |
priorityDate |
1997-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |