| abstract |
Corpuscles for implantation into or at body tissue have carriers of biologically inert material, and such carriers contain medicine which is distributed therein for release into body tissue upon completion of the implanting operation. The configuration of the carriers departs from a spherical or an exact spheroidal shape. The end sections of the carriers can have conical, frustoconical, semiellipsoidal, or semispherical shapes and can consist of pairs of identical or different segments. The central sections of the carriers can resemble barrels, or their central longitudinal cross sections can have conical, elliptical, straight or other outlines. The carriers have central or substantially central longitudinal passages for a filament which supports a surgically implantable composition constituting a row or file or string of two or more identical and/or different carriers. The transverse cross sections of the carriers can have circular, elliptical, polygonal and/or other outlines. An advantage of the corpuscles is that the surface-to-volume ratio of their carriers is more satisfactory than that of the carriers forming part of conventional corpuscles so that they can be readily withdrawn from the body. |